Ciplazidovir

Ciplazidovir may be available in the countries listed below.

Ingredient matches for Ciplazidovir

Zidovudine

Zidovudine is reported as an ingredient of Ciplazidovir in the following countries:

• Colombia

International Drug Name Search

Recofol

Recofol may be available in the countries listed below.

Ingredient matches for Recofol

Propofol

Propofol is reported as an ingredient of Recofol in the following countries:

• Algeria


• Bangladesh


• Bosnia & Herzegowina


• Finland


• Indonesia


• Israel


• Malta


• Oman


• Romania


• Russian Federation


• Serbia


• Singapore


• South Africa


• Spain


• Taiwan


• Tunisia


• Turkey

International Drug Name Search

Revalor XS

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Revalor XS

Estradiol

Estradiol is reported as an ingredient of Revalor XS in the following countries:

• United States

Trenbolone

Trenbolone 17ß-acetate (a derivative of Trenbolone) is reported as an ingredient of Revalor XS in the following countries:

• United States

International Drug Name Search

Tetryzoline

In some countries, this medicine may only be approved for veterinary use.

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R01AA06,R01AB03,S01GA02

CAS registry number (Chemical Abstracts Service)

0000084-22-0

Chemical Formula

C13-H16-N2

Molecular Weight

200

Therapeutic Category

Vasoconstrictor ORL, local

Chemical Name

1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-

Foreign Names

• Tetryzolinum (Latin)
• Tetryzolin (German)
• Tétryzoline (French)
• Tetrizolina (Spanish)

Generic Names

• Tetrahydrozoline (OS: BAN)
• Tetrizolina (OS: DCIT)
• Tetryzoline (OS: BAN)
• Tétryzoline (OS: DCF)
• Tetrahydrozolini chloridum (IS)
• Tetrahydrozoline Hydrochloride (PH: USP 32)
• Tetryzoline Hydrochloride (PH: BP 2010, Ph. Eur. 6)
• Tetryzolini hydrochloridum (PH: Ph. Eur. 6)

Brand Names

• ABC
  Harasawa Seiyaku, Japan



• Colirio Eyemo
  Farpasa, Peru



• Efemolina (Tetryzoline and Fluorometholone)
  Novartis Pharmaceuticals, Peru



• International Apex Tetrahydrozoline
  Duopharma, Philippines



• Murine Plus
  Abbott, Peru



• Narbel
  Nitto Medic, Japan



• Octilia
  Sifi, Peru



• Spersallerg (Tetryzoline and Antazoline)
  Novartis, Slovenia



• Stilla
  Teva, Israel



• Alarm (veterinary use)
  Laboratoire TVM, France



• Allergopos (Tetryzoline and Antazoline)
  Ursapharm, Germany



• Apillerg (Tetryzoline and Antazoline)
  Amman Pharmaceutical Industries Co., Oman



• Azoline
  Fischer, Israel



• Azulina Llorens
  Llorens, Spain



• Bano
  Poen, Argentina



• Berberil N
  Mann, Luxembourg; Mann, Taiwan



• Berberil
  Dr. Mann, Poland



• Berberil EDO
  Mann, Germany



• Biorinil (Tetryzoline and Betamethasone)
  Thea, Italy



• Braito
  Konimex, Myanmar



• Burnil
  Kurtsan, Turkey



• Chiosan
  Lafedar, Argentina



• Colircusi Medrivas (Tetryzoline and Medroxyprogesterone)
  Alcon, Spain



• Colirio Llorens Fluorvas (Tetryzoline and Fluorometholone)
  Llorens, Spain



• Collypan (Tetryzoline and Zinc Sulfate)
  Vifor, Switzerland



• Collyrium
  Bausch & Lomb, United States



• Cor Tyzine (Tetryzoline and Prednisolone)
  Yoshindo, Japan



• Croma (Tetryzoline and Cromoglicic Acid)
  Jamjoom Pharma, Oman



• Cromozil (Tetryzoline and Cromoglicic Acid)
  Tubilux, Italy



• Demetil
  Thea-F, Italy



• Efemolin (Tetryzoline and Fluorometholone)
  Novartis, Germany



• Efemoline (Tetryzoline and Fluorometholone)
  Novartis, Switzerland; Novartis, Greece; Novartis, Italy



• Eyedec
  Johnson & Johnson, Italy



• Eye-Mo
  GlaxoSmithKline, Philippines



• Eye-Visol
  Bilim, Turkey



• Flumezina (Tetryzoline and Fluorometholone)
  Thea-F, Italy



• Gemini (Tetryzoline and Antazoline)
  Adcock Ingram Pharmaceuticals, South Africa



• Ischemol A (Tetryzoline and Chlorphenamine)
  Thea-F, Italy



• Isotic Clearin
  Fahrenheit, Indonesia



• Ivysine
  Ivee Aqua, Ethiopia



• Montevizin
  Hemomont, Serbia



• Murine Plus
  Abbott Laboratories, Ethiopia; Prestige Brands, United States



• Murine Sore Eyes
  Aspen, Australia



• Octilia
  Bouty, Italy; Zambon, Russian Federation



• Ocudiafan
  Biosintex, Argentina



• Oculerge (Tetryzoline and Antazoline)
  Aspen Pharmacare Consumer, South Africa



• Oftan Starine
  Santen, Finland



• Oftizoline
  Bestpharma, Chile



• Ophtalmin
  Winzer, Germany



• Optigene
  Pfeiffer, United States



• Optizoline
  Xepa-Soul Pattinson, Hong Kong



• Piam
  Denver, Argentina



• Rhinal
  Zentiva, Slovakia



• Santo
  Sanbe, Indonesia



• Sensilux
  Unimed, Slovakia; Unimed Pharma, Bulgaria



• Sinutab NS
  Pfizer, Philippines



• Spersallerg (Tetryzoline and Antazoline)
  Adcock Ingram Pharmaceuticals, South Africa; Excelvision, Bulgaria; Novartis, Switzerland; Novartis, Germany; Novartis, Norway; Novartis, Oman; Novartis, Poland; Novartis, Slovakia



• Starazolin
  Polpharma, Poland



• Stilla Decongestionante
  Abic, Israel; Angelini, Italy



• Tetrahydrozoline Hydrochloride
  Rugby, United States



• Tetrilin
  CNP, Germany



• Tetryvil
  Hasco, Poland



• Tetryzolin DMP
  Mann, Germany



• Tyzine
  Johnson & Johnson, Hungary; Nycomed, United States; Pfizer, Bosnia & Herzegowina; Pfizer, Georgia; Pfizer, Romania; Pfizer, Russian Federation



• Vasodexa Llorens (Tetryzoline and Dexamethasone)
  Llorens, Spain



• Vasopos
  Ursapharm, Czech Republic; Ursapharm, Germany; Ursapharm, Romania



• Vasorinil
  Sinclair, Italy



• Visiclear
  Pfizer, Slovenia



• Visine
  Johnson & Johnson, Australia; Johnson & Johnson, Croatia (Hrvatska); Johnson & Johnson, Hungary; Johnson & Johnson, New Zealand; McNeil, Belgium; Pfizer, Czech Republic; Pfizer, Estonia; Pfizer, Egypt; Pfizer, Finland; Pfizer, Georgia; Pfizer, Ghana; Pfizer, Hong Kong; Pfizer, Israel; Pfizer, India; Pfizer, Kenya; Pfizer, Liberia; Pfizer, Lithuania; Pfizer, Latvia; Pfizer, Malawi; Pfizer, Nigeria; Pfizer, Philippines; Pfizer, Poland; Pfizer, Portugal; Pfizer, Romania; Pfizer, Serbia; Pfizer, Russian Federation; Pfizer, Sudan; Pfizer, Slovakia; Pfizer, Sierra Leone; Pfizer, Thailand; Pfizer, Turkey; Pfizer, United States; Pfizer, Vietnam; Pfizer Consumer Health, Singapore; Pfizer Pharma, Ethiopia; Roerig, Chile



• Visine Allergy (Tetryzoline and Zinc Sulfate)
  Johnson & Johnson, Canada



• Visine Classic
  Janssen-Cilag, Switzerland



• Visine Cool Eye Drops (Tetryzoline and Macrogol)
  Johnson & Johnson, Canada



• Visine Original
  Johnson & Johnson, Canada



• Visine Visiclear
  McNeil, Denmark



• Visine Yxin ED
  McNeil, Germany



• Visional
  Maver, Chile



• Visol
  Blim Pharmaceuticals, Ethiopia



• Vispring
  Pfizer Consumer Healthcare, Spain



• Visto
  Global Multi Pharmalab, Indonesia



• Visubril
  Allergan, Argentina



• Visustrin
  Pietrasanta, Italy



• Vizine
  Pfizer, Bosnia & Herzegowina



• V-Zoline
  Vitamed, Israel



• Zalbion
  Bioton, Poland

International Drug Name Search

Glossary

BAN	British Approved Name
DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

ondansetron injection

Generic Name: ondansetron (injection) (on DAN se tron)

Brand Names: Zofran

What is ondansetron?

Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting.

Ondansetron injection is used to prevent nausea and vomiting that may be caused by surgery or medicine to treat cancer (chemotherapy).

Ondansetron injection may also be used for purposes not listed in this medication guide.

What is the most important information I should know about ondansetron?

You should not use ondansetron if you are allergic to it, or if you are also using apomorphine (Apokyn). Ondansetron can cause serious heart rhythm problems. You should not use this medication if you have a history of Long QT syndrome. Tell your doctor if anyone in your family has ever had this condition.

Before receiving ondansetron injection, tell your doctor if you have liver disease, heart disease, a heart rhythm disorder, congestive heart failure, or low potassium or magnesium levels in your blood.

Tell your doctor about all other medicines you use. There are many other medicines that can increase your risk of heart rhythm problems if you use them together with ondansetron.

Call your doctor at once if you have fast, slow, or uneven heartbeats, or if you feel like you might pass out.

What should I discuss with my healthcare provider before taking ondansetron?

You should not use ondansetron if you are allergic to it, or if you are also using apomorphine (Apokyn). Ondansetron can cause serious heart rhythm problems. You should not use this medication if you have a history of Long QT syndrome. Tell your doctor if anyone in your family has ever had this condition.

To make sure you can safely receive ondansetron injection, tell your doctor if you have any of these other conditions:

• 
  

  liver disease;

  
  


• 
  

  a serious heart condition or heart rhythm disorder;

  
  


• 
  

  slow or fast heartbeats, or heart block;

  
  


• 
  

  congestive heart failure;

  
  


• 
  

  an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or

  
  


• 
  

  if you are allergic to medicines similar to ondansetron, such dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).

  
  

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take ondansetron?

Ondansetron is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Ondansetron must be given slowly, and the IV infusion can take up to 15 minutes to complete.

Ondansetron is usually given just before your surgery begins, or within 2 hours after surgery.

To prevent nausea and vomiting caused by chemotherapy, ondansetron is given 30 minutes before the start of chemotherapy. A second and third dose of ondansetron are sometimes given 4 hours and 8 hours after the first dose.

Ondansetron injection is not for preventing nausea or vomiting that is caused by factors other than chemotherapy or surgery.

See also: Ondansetron dosage (in more detail)

What happens if I miss a dose?

Since ondansetron is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while taking ondansetron?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Ondansetron side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  fast, slow, or uneven heartbeats;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;

  
  

Less serious side effects may include:

• 
  

  diarrhea, constipation;

  
  


• 
  

  drowsiness;

  
  


• 
  

  itching, numbness, or tingling;

  
  


• 
  

  mild headache; or

  
  


• 
  

  fever, or cold feeling.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Ondansetron Dosing Information

Usual Adult Dose for Nausea/Vomiting -- Chemotherapy Induced:

Initial: 0.15 mg/kg IV given 30 minutes before the start of emetogenic therapy, then repeat the dose at 4 hour intervals for 2 additional doses. A continuous IV dose option consists of 8 mg followed by 1 mg/hr for the next 24 hours.

Alternative therapies:
With highly emetogenic chemotherapy, give a onetime IV dose of 32 mg, 30 minutes before the start of single-day therapy; Infuse over 15 minutes. Alternatively, give a single 24 mg orally 30 minutes before therapy.
With moderate emetogenic chemotherapy, give 8 mg orally 30 minutes before the start of therapy, then 8 mg given 8 hours after the first dose. Thereafter, give 8 mg every 12 hours for 1 to 2 days after emetogenic therapy is complete.

Oral soluble film dosage form: Highly emetogenic cancer chemotherapy: 24 mg given successively as three 8 mg films administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m2. Moderately emetogenic cancer chemotherapy: One 8 mg soluble film given 2 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose.

Usual Adult Dose for Nausea/Vomiting:

Initial: 0.15 mg/kg IV given 30 minutes before the start of emetogenic therapy, then repeat the dose at 4 hour intervals for 2 additional doses. A continuous IV dose option consists of 8 mg followed by 1 mg/hr for the next 24 hours.

Alternative therapies:
With highly emetogenic chemotherapy, give a onetime IV dose of 32 mg, 30 minutes before the start of single-day therapy; Infuse over 15 minutes. Alternatively, give a single 24 mg orally 30 minutes before therapy.
With moderate emetogenic chemotherapy, give 8 mg orally 30 minutes before the start of therapy, then 8 mg given 8 hours after the first dose. Thereafter, give 8 mg every 12 hours for 1 to 2 days after emetogenic therapy is complete.

Oral soluble film dosage form: Highly emetogenic cancer chemotherapy: 24 mg given successively as three 8 mg films administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m2. Moderately emetogenic cancer chemotherapy: One 8 mg soluble film given 2 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose.

Usual Adult Dose for Nausea/Vomiting -- Postoperative:

4 mg IV (undiluted) over 2 to 5 minutes, or IM, immediately before induction of anesthesia or postoperatively if nausea or vomiting occurs immediately after surgery. Alternatively, 16 mg orally 1 hour before induction of anesthesia.

Oral soluble film dosage form: 16 mg given as successively as two 8 mg oral soluble films 1 hour before induction of anesthesia.

Usual Adult Dose for Nausea/Vomiting--Radiation Induced:

8 mg orally every 8 hours, give the first dose 1 to 2 hours prior to radiotherapy.

Oral soluble film dosage form:
One 8 mg soluble film given 3 times a day.
For total body irradiation: One 8 mg soluble film given 1 to 2 hours before each fraction of radiotherapy administered each day.
For single high-dose fraction radiotherapy to the abdomen: One 8 mg oral soluble film given 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for 1 to 2 days after completion of radiotherapy.
For daily fractionated radiotherapy to the abdomen: One 8 mg oral soluble film given 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for each day radiotherapy is given.

Usual Adult Dose for Pruritus:

Study (n=150) - Induced by Intrathecal Fentanyl
8 mg IV before spinal anesthesia.

Usual Adult Dose for Alcohol Dependence:

Study (n=321) - Early onset alcoholism
4 mcg/kg two times daily.

Usual Adult Dose for Postanesthetic Shivering:

Study (n=82)
8 mg IV, 3 to 5 minutes before the induction of anesthesia.

Usual Pediatric Dose for Nausea/Vomiting -- Postoperative:

Child 1 month to 12 years:
40 kg or less: 0.1 mg/kg single dose IV, administered over 2 to 5 minutes, immediately prior to or following anesthesia induction, or postoperatively if nausea and/or vomiting present shortly after surgery.

40 kg or more: 4 mg single dose IV, administered over 2 to 5 minutes, immediately prior to or following anesthesia induction, or postoperatively if nausea and/or vomiting present shortly after surgery.

Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:

Child 6 months to 18 years: 0.15 mg/kg as an IV infusion (over 15 minutes) administered 30 minutes before the start of emetogenic therapy, then at 4 and 8 hours after the first dose, respectively.

4 to 11 years: 4 mg orally given 30 minutes before the start of emetogenic therapy, then 4 mg orally 4 and 8 hours after the first dose. Thereafter, 4 mg orally every 8 hours for 1 to 2 days after emetogenic therapy is complete.

11 years or older:: 8 mg orally 3 times daily, or 24 mg orally once daily.

Oral soluble film dosage form: Use of ondansetron oral soluble films is not indicated for treatment of nausea and vomiting associated with highly emetogenic cancer chemotherapy in pediatric patients.
For prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy: For pediatric patients 12 years of age and older, the dosage is the same as for adults. For pediatric patients 4 through 11 years of age, the dosage is one 4 mg oral soluble film given 3 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with subsequent doses 4 and 8 hours after the first dose. One 4 mg oral soluble film should be administered 3 times a day (every 8 hours) for 1 to 2 days after completion of chemotherapy.

Usual Pediatric Dose for Gastroenteritis:

Study (n=145) - Control of emesis during the ED phase of oral rehydration:
6 months to 12 months: 1.6 mg orally every 8 hours
1 year to 3 years: 3.2 mg orally every 8 hours
4 years or older: 4 mg orally every 8 hours

Dosage was administered 15 minutes before the start of oral rehydration.

What other drugs will affect ondansetron?

There are many other medicines that can increase your risk of heart rhythm problems if you use them together with ondansetron.

Tell your doctor about all other medicines you use, especially:

• 
  

  arsenic trioxide (Trisenox);

  
  


• 
  

  tacrolimus (Prograf);

  
  


• 
  

  tramadol (Ultram);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin);

  
  


• 
  

  anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam);

  
  


• 
  

  heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace);

  
  


• 
  

  other medicines to prevent or treat nausea and vomiting such as dolasetron (Anzemet) or droperidol (Inapsine);

  
  


• 
  

  medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

  
  


• 
  

  migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig); or

  
  


• 
  

  narcotic medication such as methadone (Methadose, Diskets, Dolophine).

  
  

This list is not complete and other drugs may interact with ondansetron injection. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More ondansetron resources

• Ondansetron Side Effects (in more detail)
• Ondansetron Dosage
• Ondansetron Use in Pregnancy & Breastfeeding
• Drug Images
• Ondansetron Drug Interactions
• Ondansetron Support Group
• 81 Reviews for Ondansetron - Add your own review/rating

Compare ondansetron with other medications

• Alcohol Dependence
• Gastroenteritis
• Nausea/Vomiting
• Nausea/Vomiting, Chemotherapy Induced
• Nausea/Vomiting, Postoperative
• Nausea/Vomiting, Radiation Induced
• Obsessive Compulsive Disorder
• Postanesthetic Shivering
• Pruritus

Where can I get more information?

• Your doctor or pharmacist can provide more information about ondansetron injection.

See also: ondansetron side effects (in more detail)

App Vasopressin

App Vasopressin may be available in the countries listed below.

Ingredient matches for App Vasopressin

Vasopressin

Vasopressin is reported as an ingredient of App Vasopressin in the following countries:

• Hong Kong

International Drug Name Search

Astémizole

Astémizole may be available in the countries listed below.

Ingredient matches for Astémizole

Astemizole

Astémizole (DCF) is known as Astemizole in the US.

International Drug Name Search

Glossary

DCF	Dénomination Commune Française

Click for further information on drug naming conventions and International Nonproprietary Names.